Download Book ↠ The Family Gene Î 272 pages Ø Hannahredhead

Mobi ë The Family Gene ¸ Joselin Linder

A riveting medical mystery about a young woman’s uest to uncover the truth about her likely fatal genetic disorder that opens a window onto the exploding field of genomic medicineWhen Joselin Linder was in her twenties her legs suddenly started to swell After years of misdiagnoses doctors discovered a deadly blockage in her liver Struggling to find  an explanation for her unusual condition Joselin compared the medical chart of her father who had died from a mysterious disease ten years prior with that of an uncle who had died under simila When Joselin Linder was a teenager in the late 80s her father grew ill His symptoms—primarily that his body was swelling and his lungs were filling with fluid leaking out of his lymphatic system—confounded doctors as they didn't seem to align with any known condition There seemed to be no discernible reason for this to be happening to an otherwise healthy middle aged man And there seemed to be no way to treat his symptoms But some older relatives recognized the symptoms they were the same ones that had killed both his grandmother and his uncle in the mid 20th century Eventually the Linder family and their doctors began to realize that the condition was tied to genetics something was wrong with a gene that was being passed through this family and it was causing these symptoms As far as anyone could tell just fourteen people in the entire world had this gene—all descended from Joselin’s great great grandmother—and five had succumbed to the deadly disease that it caused By the time that Joselin's father succumbed to his illness in 1996 the medical community's understanding of genetic disorders was growing by leaps and bounds but there were still huge gaps in the knowledge As the Human Genome Project neared completion and genetic mapping became a reality medical experts studying the family began tracing the source of their disease They were looking for the exact chromosome that carried the faulty gene and trying to figure out exactly what it was doing to the body so that the fatal symptoms could be alleviated Meanwhile Joselin and her sister Hillary were struggling to reconcile their desire to start a family with the fear that this faulty gene could be passed on to their own children This is a fascinating medical mystery that will appeal to anyone who’s enjoyed books like The Immortal Life of Henrietta Lacks which Linder herself namechecks in her explanation of genetic science Though some of the science gets a bit dense—don’t expect me to clearly explain exactly what this disease was doing to the vascular system and the liver nor exactly how gene mapping works—Linder does a pretty good job distilling it down into layman’s terms After all she’s not a scientist and she’s had to figure out what’s going on inside her own body That being said the writing could be a bit clunky at times I was reading an advanced copy so it’s possible that editing was done but I also think that this book came about from some work being done for a public radio piece that was eventually got scrapped And honestly at times the sentence structure felt appropriate for a radio piece than for a book It’s hard to explain but the writing styles are understandably different between the the two mediums and it doesn’t always uite gel here Still it’s a book that will make you think Genetic diseases are absolutely terrifying Knowing that you are destined to develop a disease and there’s nothing that can be done about it? I can’t even begin to imagine how difficult it must be to process that and carry on in spite of it The science of genetics is still relatively young and it suffers to some extent from public ignorance There are some people who uestion the ethics of genetic manipulation but Linder argues that we need greater understanding of these diseases and their complicated roots She does an excellent job putting a human face and a human story on what could have easily become dry clinical science talk

Ebook The Family Gene

The Family GeneLed a private mutation meaning that they were the first known people to experience the baffling symptoms of a brand new genetic mutation Here Joselin tells the story of their gene the lives it claimed and the future of genomic medicine with the potential to save those that remain Digging into family records and medical history conducting interviews with relatives and friends and reflecting on her own experiences with the Harvard doctor Joselin pieces together the lineage of this deadly gene to write an exploration of family history and love I read this book uickly because I skimmed or skipped the essays about genetics the movie reviews and the book reports There wasn’t much left What there was of the author’s story of her family’s genetic mutation was interesting but inconclusive This was an deal that I bought for a buck or two These are always crapshoots I have realized two things from these books editors serve a vital function and reviews are unreliable I did make it all the way through this one though even though I skipped long passages

Joselin Linder ¸ The Family Gene Epub

Download Book ↠ The Family Gene Î 272 pages Ø Hannahredhead ï A riveting medical mystery about a young woman’s uest to uncover the truth about her likely fatal genetic disorder that opens a window onto the exploding field of genomic medicineWhen Joselin Linder was in her twenties her legs suddenlRly strange circumstances Delving further into the past she discovered that her great grandmother had displayed symptoms similar to hers before her death Clearly this was than a fluke Setting out to build a complete picture of the illness that haunted her family Joselin approached Dr Christine Seidman the head of a group of world class genetic researchers at Harvard Medical School for help Dr Seidman had been working on her family’s case for twenty years and had finally confirmed that fourteen of Joselin’s relatives carried something cal This review and others can be found on BW Book ReviewsThis book took me a long time to listen to because it was interrupted by my finals No work means no listening to books Even though it was good I couldn't listen to it on my free time thanks to being a responsible college student and doing this dreadful thing called studying Warn your kids about it It can get pretty terrifyingAs I said this was a good book It was fun and I really enjoyed how it was read Just very upbeat and light most of the time When this book focuses on a family illness that is currently untreatable and has killed everyone who has it the author's father uncle and other people that's really impressive It's a very light book It's fun to read or listen to because it simply flows so wellStarting in the 90s this book chronicles a family illness It begins with Joselin's father a doctor who gets ill Very ill I think ill is an understatement to it Then as he gets worse then it comes out that other people in his family had the same symptoms that he does They also died of this mystery disease They don't know what it is but know that everyone who has had it has a heart murmur testing people in the family for itAt times it was heavy with technical terms but Joselin explained them perfectly I've taken enough classes and read enough books to know most of the terms She just told it what it is in non doctor speak It's accessible to anyone really All you have to know is the basics and anything beyond it she explains Hell even the basics get explainedIt largely focuses on Joselin's experiences She's not a doctor after all She's a woman who watched various members of her family get sick and die It's focused on her experience of this and the stages of grief that she went through While I'm not sure I would have liked Joselin as a person for a good part of the story I could appreciate it She reacted in a way people only can Still hearing about her healing process didn't uite interest me as much as hearing the journey of discovery about their disorderAll in all a good book that had very minor flaws for me